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Emerging role of calprotectin in gastroenterology
Author(s) -
POULLIS ANDREW,
FOSTER RUSSELL,
MENDALL MICHAEL A,
FAGERHOL MAGNE K
Publication year - 2003
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1046/j.1440-1746.2003.03014.x
Subject(s) - calprotectin , medicine , gastroenterology , feces , faecal calprotectin , pathology , inflammatory bowel disease , disease , paleontology , biology
Calprotectin is a calcium and zinc binding protein of the S100 family derived predominantly from neutrophils and monocytes. It is detectable in body fluids and tissue samples and is emerging as a valuable marker in the diagnosis, and the monitoring and determining of the prognosis of commonly encountered gastroenterological conditions. Fecal calprotectin, in particular, has for a long time been regarded as a promising marker of gastrointestinal pathology and has now been established as a routine test in Norway and at several centers in the UK. © 2003 Blackwell Publishing Asia Pty Ltd