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Autoantibody in a patient with chronic hepatitis C virus infection showing complete remission after interferon therapy
Author(s) -
AKASHI YOSHIHIRO,
INOH MASAYUKI,
SETO KUNIO,
GAMO NAOYUKI,
KUBOKI MAKOTO,
KURATA NORIYUKI
Publication year - 2002
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1046/j.1440-1746.2002.02651.x
Subject(s) - medicine , anti nuclear antibody , autoantibody , antibody , immunology , interferon , serology , hepatitis c virus , hepatitis , virology , autoimmune hepatitis , hepatitis c , virus
A 42‐year‐old woman was admitted to Kinashi Ohbayashi Hospital for liver dysfunction. She presented with hepatitis C viral infection accompanied by autoimmune hepatitis‐like serological manifestations, such as antinuclear antibody (ANA), antismooth muscle cell antibody and especially anti‐ribonucleoprotein (RNP) antibody and anti‐SSB antibody. After interferon therapy, hepatitis C virus was not detected and ANA, anti‐RNP antibody and anti‐SSB antibody disappeared. To our knowledge, this is the first reported hepatitis C patient showing anti‐RNP antibody and anti‐SSB antibody, having complete remission after interferon therapy.