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Iron and hepatocellular carcinoma
Author(s) -
Deugnier Yves,
Turlin Bruno
Publication year - 2001
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1046/j.1440-1746.2001.02430.x
Subject(s) - hepatocellular carcinoma , medicine , hemochromatosis , gastroenterology , hereditary hemochromatosis , carcinogen , dietary iron , oncology , cancer research , iron deficiency , genetics , anemia , biology
The high prevalence of hepatocellular carcinoma (HCC) in genetic hemochromatosis (GH) and the association between increased body iron stores and occurrence of HCC in subjects with iron overload unrelated to GH, and the experimental evidence of a co‐carcinogenic role of iron strongly support that iron is involved in the development of HCC.