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Wilson’s disease presenting with rapidly progressive visual loss: Another neurologic manifestation of Wilson’s disease?
Author(s) -
Gow Paul J,
Peacock Sophie E,
Chapman Roger W
Publication year - 2001
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1046/j.1440-1746.2001.02381.x
Subject(s) - wilson's disease , medicine , disease , copper metabolism , neurologic disease , visual disturbance , optic neuropathy , central nervous system , basal ganglia , pathology , optic nerve , surgery , anatomy , copper , chemistry , organic chemistry
Wilson’s disease (WD) is a rare autosomal recessive disorder of copper metabolism resulting in copper‐induced tissue damage that primarily involves the liver and central nervous system. The neurologic manifestations of WD almost universally involve a derangement of basal ganglia function or psychiatric disturbance. We report the case of a 46‐year‐old man presenting with end‐stage liver disease caused by WD who had associated rapidly progressive optic neuropathy. We also discuss the possible association between the two conditions.