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Lupus–like syndrome with submassive hepatic necrosis associated with hepatitis A
Author(s) -
Segev Amit,
Hadari Ruth,
Zehavi Tanya,
Schneider Mordechai,
Hershkoviz Rami,
Mekori Yoseph A
Publication year - 2001
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1046/j.1440-1746.2001.02314.x
Subject(s) - medicine , autoimmune hepatitis , systemic lupus erythematosus , autoantibody , hepatitis , viral hepatitis , pleural effusion , liver disease , overlap syndrome , hepatitis c , immunology , disease , pathology , gastroenterology , antibody
Hepatitis A is a common self‐limited liver disease. However, 15% of patients may have some complications. Autoimmune hepatitis that is triggered by viral hepatitis has been reported. We hereby describe an unrecognized association of hepatitis A with a full blown lupus‐like syndrome manifested by the appearance of arthralgia, exudative pleural effusion with the presence of lupus erythematosus cells and autoantibodies. All these findings disappeared after a short course of steroid treatment. The case is presented and the literature is reviewed.