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Use of a dry latex agglutination test to measure eradication of Helicobacter pylori infection
Author(s) -
Midolo Peter D,
Dakic Bilijana,
Nicholson Lesley,
Lambert John R,
Lin Shaokai,
Russell Edward G
Publication year - 2000
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1046/j.1440-1746.2000.02081.x
Subject(s) - medicine , serology , latex fixation test , helicobacter pylori , immunoassay , antibody , spirillaceae , immunology , gastroenterology , gastritis
Background and Methods: A total antibody latex serology test was compared with enzyme immunoassay serology after treatment for Helicobacter pylori infection in 22 patients.Results: Nineteen patients were cured of infection, but only nine (47%) were negative by the latex test after 6 months. However a significant decline in immunoglobulin (Ig)G was seen in 90% of the cured patients.Conclusions: Although the latex test is suitable for initial diagnosis of H. pylori infection, it is not suitable for monitoring treatment success. A decline in IgG of more than 40% correlates well with successful eradication of H. pylori . © 2000 Blackwell Science Asia Pty Ltd