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Coagulation abnormalities in idiopathic portal venous thrombosis
Author(s) -
Ahuja Vineet,
Marwaha Neelam,
Chawla Yogesh,
Dilawari Jung Bahadur
Publication year - 1999
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1046/j.1440-1746.1999.02030.x
Subject(s) - medicine , lupus anticoagulant , portal vein thrombosis , antithrombin , thrombosis , venous thrombosis , antithrombin iii deficiency , partial thromboplastin time , bleed , gastroenterology , portal hypertension , anticoagulant , coagulation , coagulation disorder , surgery , heparin , cirrhosis
AbstractBackground: Portal vein thrombosis, usually idiopathic, is the cause of portal hypertension in 46% of Indian patients, who present with a variceal bleed. The presence of lupus anticoagulant (LA) and antithrombin III deficiency have been reported to be associated with an increased tendency to venous thrombosis.Methods and Results: We studied 30 patients with portal venous thrombosis diagnosed by ultrasound. Two patients were positive for a lupus anticoagulant and both had very prolonged partial thromboplastin time with kaolin. None of the patients had antithrombin III deficiency. © 1999 Blackwell Science Asia Pty Ltd