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Peripheral cholangiocarcinoma (cholangiocellular carcinoma): Clinical features, diagnosis and treatment
Author(s) -
Chen MiinFu
Publication year - 1999
Publication title -
journal of gastroenterology and hepatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.214
H-Index - 130
eISSN - 1440-1746
pISSN - 0815-9319
DOI - 10.1046/j.1440-1746.1999.01983.x
Subject(s) - medicine , hepatectomy , jaundice , percutaneous , intrahepatic cholangiocarcinoma , hepatocellular carcinoma , brachytherapy , radiology , histopathology , metastasis , stage (stratigraphy) , pathological , surgery , cancer , pathology , radiation therapy , resection , paleontology , biology
Peripheral cholangiocarcinoma is a relatively rare cancer. However, it is known to have an unfavourable prognosis compared with that of hepatocellular carcinoma. Little is known about its aetiology, clinical or pathological features. Recently, with the development of imaging modalities, early staged cholangiocarcinoma has been diagnosed with relative ease. Surgery is the optimal therapy. Total hepatectomy does not provide survival benefit. Conventional surgery remains the only effective treatment, even for patients with advanced‐stage tumours. Factors influencing survival after hepatectomy were tumour‐free margin, lymphnodes metastasis and histopathology of tumour. Palliative intrahepatic tubing or percutaneous transhepatic biliary drainage and brachytherapy can alleviate jaundice and cholangitis, thereby prolonging survival in some cases. © 1999 Blackwell Science Asia Pty Ltd