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Visualizing lymphocyte recognition
Author(s) -
Wülfing Christoph,
Chien YuehHsiu,
Davis Mark M
Publication year - 1999
Publication title -
immunology and cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0818-9641
DOI - 10.1046/j.1440-1711.1999.00813.x
Subject(s) - focus (optics) , cognitive science , t cell receptor , biology , computational biology , computer science , t cell , genetics , psychology , immune system , physics , optics
Studies of T cell recognition have entered new territory now that some of the basic issues of genetics, biochemistry and structure have been addressed, at least in outline form. In the present work, the focus is on a new aspect of T cell recognition that goes beyond classical biochemistry to ask, ‘how do TCR and other cell surface molecules cooperate to initiate and control recognition?’