Premium
Suppressors of the vestigial mutant phenotype increase the level of expression of the gene
Author(s) -
Flagiello Domenico,
Fellini Nadia,
Cibert Christian,
Zider Alain,
Cavicchi Sandro,
Silber Joel
Publication year - 1996
Publication title -
development, growth and differentiation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.864
H-Index - 66
eISSN - 1440-169X
pISSN - 0012-1592
DOI - 10.1046/j.1440-169x.1996.t01-4-00012.x
Subject(s) - phenotype , mutant , genetics , gene , biology , suppressor , expression (computer science) , gene expression , microbiology and biotechnology , computer science , programming language
Suppressor genes of the vestigial phenotype have been isolated in a wild‐type population. These suppressors have an effect on different wing mutants and are allele‐specific in the case of vestigial . In a vg BG background they produced overgrowth of the imaginal wing disc. They also induce cell death in the wild‐type strain and alter the distribution of cell death in the mutant strain. Expression of vestigial is increased in the wing disc only. Hypotheses formed to determine the nature of these suppressors are in favor of a direct interaction between these genes and vestigial .