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Prenatal Exposure To Magnetic Field Increases Dopamine Levels In The Striatum Of Offspring
Author(s) -
Lee ByungCheon,
Bing Guoying,
Jhoo WangKee,
Yoon JooMae,
Kang KeeSeok,
Shin EunJoo,
Kim WonKi,
Ko Kwang Ho,
Kim HyoungChun
Publication year - 2001
Publication title -
clinical and experimental pharmacology and physiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.752
H-Index - 103
eISSN - 1440-1681
pISSN - 0305-1870
DOI - 10.1046/j.1440-1681.2001.03538.x
Subject(s) - offspring , dopamine , striatum , gestation , metabolite , prenatal exposure , endocrinology , 3,4 dihydroxyphenylacetic acid , medicine , pregnancy , physiology , chemistry , homovanillic acid , biology , serotonin , genetics , receptor
SUMMARY 1. The putative effects of prenatal exposure to magnetic field (MF) have recently received much interest. In the present study, mice were exposed to a MF of 50 mT during gestation (0–19 days). 2. After the exposure was terminated, mothers and offspring were returned to normal laboratory conditions. We then determined changes in striatal levels of dopamine (DA) and its metabolite 3,4‐dihydroxyphenylacetic acid (DOPAC) in the offspring. 3. Our results indicate that prenatal exposure to MF increases levels of DA and DOPAC in the striatum at 4, 8 and 12 weeks postnatally.