Premium
Phenytoin‐induced linear IgA dermatosis mimicking toxic epidermal necrolysis
Author(s) -
Tran Diana,
Kossard Steven,
Shumack Stephen
Publication year - 2003
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1046/j.1440-0960.2003.00011.x
Subject(s) - toxic epidermal necrolysis , phenytoin , medicine , dermatology , erythroderma , epilepsy , psychiatry
SUMMARY A 60‐year‐old woman developed a severe widespread blistering eruption that also involved the palms and soles, but spared the mucosae, approximately 7 days after starting phenytoin. Phenytoin was commenced postoperatively after a craniotomy resection of a glioblastoma multiforme. The clinical features resembled that seen in toxic epidermal necrolysis. However, the patient was systemically well and the histology and immunofluorescence revealed linear IgA dermatosis. The skin lesions began to slowly heal 2 weeks after discontinuation of the phenytoin.