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Porokeratosis of Mibelli: Successful treatment with topical 5% imiquimod cream
Author(s) -
Harrison Shan,
Sinclair Rodney
Publication year - 2003
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1046/j.1440-0960.2003.00010.x
Subject(s) - medicine , porokeratosis , imiquimod , cryotherapy , lesion , dermatology , curettage , occlusion , biopsy , surgery , keratosis , radiology
SUMMARY A 77‐year‐old woman with a large porokeratosis of Mibelli on the left shin was successfully treated with topical 5% imiquimod cream applied to the entire lesion once daily without occlusion three times a week. A strong inflammatory reaction was achieved in 6 weeks of treatment. The lesion had been present for approximately 6 years and prior treatments included curettage and electrocautery, cryotherapy and topical 5‐fluorouracil under occlusion. At the end of treatment with topical 5% imiquimod cream, punch biopsy was negative for porokeratosis. The lesion healed without scarring. At 24‐month follow up there had been no sign of clinical recurrence.