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Short‐term resolution of psoriasis after total thyroidectomy for euthyroid multinodular goitre
Author(s) -
Kuchel Johanna,
Barakate Michael,
Delbridge Leigh,
Agarwal Gaurav,
Beattie John,
Barnetson Ross
Publication year - 2002
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1046/j.1440-0960.2002.00599.x
Subject(s) - medicine , psoriasis , multinodular goitre , euthyroid , thyroidectomy , surgery , thyroid disease , thyroid , dermatology
SUMMARY A 36‐year‐old Chinese female with an 8‐year history of chronic, generalized plaque psoriasis demonstrated a marked improvement of the disease after removal of an intercurrent euthyroid multinodular goitre. Thyroxine was commenced immediately postoperatively. No thyroid antibodies were detected and thyroid function and calcium levels remained within normal limits both pre‐ and postoperatively. Four weeks following surgery, narrow‐band ultraviolet B (nbUVB) therapy was recommenced for recurrent psoriasis. The manifestations of psoriasis at this stage were less severe than before thyroidectomy and responded well to treatment, whereas before surgery the response to therapy had been poor. One year following total thyroidectomy, the patient received very effective psoriasis control with nbUVB therapy. The possible role of surgery and thyroid hormones in altering the pathogenesis of psoriasis in the acute setting is clearly of interest and warrants further research consideration.