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Sarcoidosis with prominent giant cells
Author(s) -
Drummond Catherine,
Savdie Elliott,
Kossard Steven
Publication year - 2001
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1046/j.1440-0960.2001.00539.x
Subject(s) - medicine , sarcoidosis , giant cell , hypercalcaemia , pathology , dermatology , calcium
SUMMARY A 31‐year‐old man presented with a widespread papular eruption and systemic symptoms including renal colic and decreased exercise tolerance. The combination of clinical features and laboratory investigations that revealed an elevated angiotensin converting enzyme level and hypercalcaemia enabled a diagnosis of sarcoidosis to be made. Multiple skin biopsies showed prominent Touton‐like giant cells which delayed the diagnosis. Giant cells are frequently seen in sarcoidal granulomas but in some cases their prominence and Touton‐like appearance may suggest alternative diagnoses such as xanthogranulomas.