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CASE REPORT Treatment of refractory hand warts by isolated limb infusion with melphalan and actinomycin D
Author(s) -
Damian Diona L,
Barnetson Ross St C,
Rose Barbara R,
Bonenkamp Johannes J,
Thompson John F
Publication year - 2001
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1046/j.1440-0960.2001.00490.x
Subject(s) - medicine , melphalan , refractory (planetary science) , chemotherapy , erythema , surgery , dermatology , physics , astrobiology
SUMMARY We present an immunocompetent man with extensive warts on the hands, refractory to a number of conventional treatment modalities and causing substantial morbidity and impairment of normal function. Isolated limb infusion (regional intra‐arterial chemotherapy) with melphalan and actinomycin D was performed, with substantial clearing of the warts within 2 months. Treatment‐induced morbidity was limited to mild local erythema and oedema which resolved within 3 weeks. After 9 months’ follow up, the patient had only a few residual warts and was able to resume normal activities.