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Oestrogen dermatitis
Author(s) -
Kumar Ajay,
Georgouras Katherine Evelyn
Publication year - 1999
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1046/j.1440-0960.1999.00329.x
Subject(s) - medicine , trunk , papule , tamoxifen , dermatology , biopsy , rash , menstruation , skin biopsy , erythema , surgery , gynecology , pathology , breast cancer , cancer , lesion , ecology , biology
A 36‐year‐old woman presented with a recurrent itchy eruption mainly involving her face and upper trunk for 5 years. The rash flared cyclically 3 days before her menstruation and improved 5–10 days after the onset of her period. Examination revealed erythematous maculopapules, vesicles and crusting mainly on her face and upper trunk. Biopsy from a papule revealed spongiotic dermatitis. Intradermal testing with oestrogen was positive. There was marked improvement with tamoxifen. Sensitivity to oestrogen and progesterone is rare in women and the clinical presentation may be similar. Positive intradermal testing is diagnostic. Tamoxifen is effective in treating oestrogen sensitivity.