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Specific skin lesions occurring in a patient with Hodgkin’s lymphoma
Author(s) -
Pagliaro John A,
White Stephen I
Publication year - 1999
Publication title -
australasian journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.67
H-Index - 53
eISSN - 1440-0960
pISSN - 0004-8380
DOI - 10.1046/j.1440-0960.1999.00315.x
Subject(s) - medicine , cd15 , lymphoma , lymph , cd30 , axillary lymph nodes , lymphatic system , reed–sternberg cell , pathology , lymphatic disease , hodgkin's lymphoma , axillary lymphadenopathy , hodgkin lymphoma , metastasis , cd34 , genetics , stem cell , cancer , breast cancer , biology
A 47‐year‐old man presented with a several month history of non‐specific acquired ichthyosis, an unknown period of generalized lymphadenopathy and a short history of erythematous papules and nodules affecting the cutaneous drainage area of his right axillary lymph nodes. Histology confirmed these lesions to be specific lesions of Hodgkin’s lymphoma; that is, metastatic retrograde lymphatic spread from his axillary lymph nodes of CD30 + , CD15 + , Reed–Sternberg cells as well as mononuclear Hodgkin’s cells. This is the most common site and mode of spread of Hodgkin’s disease to the skin. As is typical of advanced Hodgkin’s disease, as evidenced by specific cutaneous involvement, this patient died shortly after definitive diagnosis was made.