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What is the significance of an isolated positive cryptococcal antigen in the cerebrospinal fluid of cancer patients?
Author(s) -
Kontoyiannis Dimitrios P.
Publication year - 2003
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1046/j.1439-0507.2003.00877.x
Subject(s) - cerebrospinal fluid , titer , malignancy , medicine , antigen , clinical significance , cancer , pathology , immunology , antibody
Summary We evaluated the significance of an isolated positive cryptococcal antigen titer in the cerebrospinal fluid (CSF) of 12 cancer patients. In most of the cases, the test had a low titer, was frequently associated with an intracranial malignancy and was considered to represent a false‐positive result. Hence, an isolated cryptococcal antigen in the CSF has an unclear clinical value and must be interpreted with caution.