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Fallbericht. Kutane Cryptococcose bei einer Patientin mit systemischem Lupus erythematodes
Author(s) -
Ramos L.,
López C.,
Gómez C.,
Mathurín S.,
Mateo A.
Publication year - 2001
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1046/j.1439-0507.2001.00661.x
Subject(s) - medicine , cryptococcosis , dermatology , amphotericin b , skin biopsy , cellulitis , systemic disease , cryptococcus neoformans , nephrotic syndrome , systemic lupus erythematosus , cryptococcus , pathology , biopsy , immunopathology , antifungal , disease , biology , microbiology and biotechnology , genetics
Summary. The first case of a cutaneous cryptococcosis associated with systemic erythematous lupus (SLE) diagnosed in our Mycology Reference Centre is presented: a 24‐year‐old female patient diagnosed with SLE, nephrotic syndrome, arterial hypertension, renal insufficiency due to glomerulonephritis type IV and cellulitis in the right thigh and gluteus. Cryptococcus neoformans was isolated by cutaneous biopsy and haemoculture. Cryptococcal antigen was detected in serum by the latex agglutination test. As the patient did not respond to fluconazol intravenous treatment, amphotericin B administration was performed. She died of acute renal insufficiency.