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Funguria and Candida ‐specific immunoglobulins in patients with systemic candidosis
Author(s) -
Knoke M.,
Bernhardt Hannelore,
Schulz Katrin,
Schröder Gudrun,
Zimmermann Kathrin
Publication year - 2000
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1046/j.1439-0507.2000.00559.x
Subject(s) - candida glabrata , candida albicans , antibody , medicine , serology , urine , systemic candidiasis , urinary system , candida infections , immunology , mycosis , microbiology and biotechnology , gastroenterology , corpus albicans , biology
Funguria, indirect anti‐ Candida haemagglutination test (C‐IHT) and Candida ‐specific immunoglobulins C‐IgM, C‐IgG and C‐IgA were investigated under suspicion of systemic candidosis in critically ill patients. A total of 143 urine cultures were studied for Candida from 74 adults and a median count of log 3.0 CFU ml −1 was found. Most isolated Candida species were Candida albicans and Candida glabrata . In 14 cases of candidaemia there was no regular agreement between the finding of Candida species in blood and urine. In cases with candiduria ≥log 3.0 CFU ml −1 a stronger increase of C‐IHT titres and all three Candida ‐specific immunoglobulins after 5–7 days was observed. Some statistically significant correlations were found between the levels of urinary yeast counts and immunological parameters concerning C‐IHT, C‐IgA and C‐IgG on the first day and after 5–7 days. Clinical findings in some cases coincided well with funguria and courses of titres before and after treatment.