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Non‐randomized comparison of surgical modalities for paranasal sinus mycoses with intracranial extension
Author(s) -
Ashok Gupta,
S. B. S. Mann,
Virender K. Khosla,
K. V. S. S. R. K. Sastry,
Jasmine Hundal
Publication year - 1999
Publication title -
mycoses
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 69
eISSN - 1439-0507
pISSN - 0933-7407
DOI - 10.1046/j.1439-0507.1999.00470.x
Subject(s) - medicine , paranasal sinuses , paranasal sinus diseases , sinus (botany) , randomized controlled trial , radiology , surgery , biology , botany , genus
Mycotic infections of paranasal sinuses are frequently reported in southern Asia. Aspergillus and Mucor species are the predominant ones. Intracranial extension of paranasal sinus mycoses is a difficult problem to manage. We report 18 cases of paranasal sinus mycoses with intracranial extensions. The commonest manifestations were nasal discharge (67%), nasal obstruction (50%), ocular symptoms such as proptosis (44%), telecanthus (39%) and ophthalmoplegia. Computerized tomography scans were found to be quite informative regarding the nature and extent of the disease (100% sensitivity and 78% specificity). A combined intracranial–extracranial approach (six cases) gave a distinct advantage over only adopting an extracranial approach (12 cases). A 17% incidence of CSF leak was noted by adopting only an extracranial approach as well as a recurrence in four cases out of the 12 that were treated using this method ( P <0.05). A slight increase in morbidity was associated with the combined intracranial–extracranial treatment, but no recurrence or significant complications were noted in this approach.