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Estimation of the proportion of body fat in mice from the proportion of body water
Author(s) -
Terpstra A. H. M.
Publication year - 2003
Publication title -
journal of animal physiology and animal nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.651
H-Index - 56
eISSN - 1439-0396
pISSN - 0931-2439
DOI - 10.1046/j.1439-0396.2003.00413.x
Subject(s) - body water , classification of obesity , zoology , body adiposity index , regression analysis , body fat percentage , body weight , linear regression , biology , chemistry , body mass index , fat mass , endocrinology , mathematics , statistics
Summary We compared the proportion of body fat in mice as measured by chemical analysis with that estimated from the proportion of body water. First, we measured the proportion of fat by chemical analysis in 78 mice that had a proportion of body fat in the range from approximately 5 to 20%. Then, we constructed a regression line that described the relationship between the proportion of body water and the proportion of body fat by using data from several other published studies in mice (% body fat = −1.20 × % body water + 88.07, r = 0.9597, s y . x = 2.75, p < 0.001). With this regression line, we estimated the proportion of body fat from the proportion of body water that was measured by drying the carcasses at 60 °C for 3 days. Body fat data obtained from this regression line were similar to those obtained by chemical analysis. Thus, these results suggest that reliable values for the proportion of body fat can be derived from the proportion of body water and this method provides a tool to rapidly measure the proportion of body fat in mice.