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17 α‐oestradiol and 17 β‐oestradiol do not affect basal and follicle‐stimulating hormone‐stimulated inhibin B secretion by highly purified rat Sertoli cells
Author(s) -
Berlau J.,
Roemer W.,
Oettel M.,
Hipler U. C.,
Patchev V.,
Schreiber G.
Publication year - 2000
Publication title -
andrologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.633
H-Index - 59
eISSN - 1439-0272
pISSN - 0303-4569
DOI - 10.1046/j.1439-0272.2000.00354.x
Subject(s) - sertoli cell , medicine , endocrinology , follicle stimulating hormone , secretion , basal (medicine) , alpha (finance) , hormone , testicle , beta (programming language) , follicle , chemistry , biology , spermatogenesis , luteinizing hormone , construct validity , nursing , insulin , computer science , programming language , patient satisfaction
The effects of 17 α‐oestradiol and 17 β‐oestradiol on basal and follicle‐stimulating hormone (FSH)‐stimulated inhibin B secretion by rat Sertoli cells were studied. Sertoli cells were isolated and cultivated from testes of 18‐day‐old Wistar rats in the presence and absence of FSH and different doses of oestrogens. On day 4 of culture, secreted inhibin was measured by enzyme‐linked immunosorbent assay. Neither 17 α‐oestradiol nor 17 β‐oestradiol had any effect on the secreted inhibin level in either the presence or absence of FSH. It is concluded that these oestradiols do not play an essential role in regulatory processes involving inhibin or FSH.