Open AccessRoles of homocysteine in cell metabolism
Author(s) -
Medina Miguel Á.,
Urdiales José L.,
AmoresSánchez María I.
Publication year - 2001
Publication title -
european journal of biochemistry
Language(s) - English
Resource type - Journals
eISSN - 1432-1033
pISSN - 0014-2956
DOI - 10.1046/j.1432-1327.2001.02278.x
Subject(s) - hyperhomocysteinemia , homocysteine , pathogenesis , metabolism , risk factor , disease , pathogenicity , medicine , biology , microbiology and biotechnology
Mild hyperhomocysteinemia has been suggested as a new, independent risk factor for cardiovascular disease. This fact has produced a new, increased interest in the study of homocysteine metabolism and its relation to pathogenesis. This emergent area of biomedical research is reviewed here, stressing the biochemical and metabolic basis of the pathogenicity of increased levels of homocysteine.