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False‐reactive test for hepatitis B surface antigen following administration of granulocyte–colony‐stimulating factor
Author(s) -
Warren K.,
Eastlund T.
Publication year - 2002
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1046/j.1423-0410.2002.00216.x
Subject(s) - hbsag , medicine , granulocyte colony stimulating factor , granulocyte , immunology , antigen , hepatitis b , gastroenterology , hepatitis b virus , chemotherapy , virus
Background and Objective High‐dose granulocyte transfusions are being administered to severely granulocytopenic patients. A single dose of G–CSF is given to donors for mobilization of granulocytes prior to donation. Materials and Methods Infectious disease tests were performed on a donor before and after G–CSF was given. Results Hepatitis B surface antigen (HBsAg) testing was transiently reactive following administration of G–CSF when examined using a test kit from one manufacturer, but not another. No other cause was found. Conclusion A false‐reactive test for HBsAg using one manufacturer's test kit can occur following a single dose of G–CSF.