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Reduction of Platelet Transfusion Associated Sepsis by Short‐Term Bacterial Culture
Author(s) -
Liu Hingwing,
Yuen Kwokyung,
Cheng Tammy Shuiying,
Lee Kwanbun,
Chua Elizabeth Kinming,
Ho Pakleung,
Lin Chekit
Publication year - 1999
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1046/j.1423-0410.1999.7710001.x
Subject(s) - platelet , sepsis , medicine , platelet transfusion , blood culture , contamination , microbiological culture , microbiology and biotechnology , immunology , biology , bacteria , antibiotics , ecology , genetics
Background and Objectives:There is as yet no suitable routine laboratory test for a blood transfusion service to detect bacterial contamination in platelets. This study evaluates the effectiveness and the applicability of short‐term bacterial culture for such a purpose. Materials and Methods: Samples from 5‐unit platelet pools were inoculated into an aerobic culture bottle, then monitored for 48 h at 35°C in an automated monitoring and detection system. Results: 26,210 whole‐blood‐derived platelet components were tested, of which 14 (0.053%) platelet units were found to be contaminated. In addition, nine of the associated red cell units and 4 fresh‐frozen plasma units grew the same organisms on culture. Conclusion: Short‐duration bacterial culture by an automated system is effective and suitable for routine screening in a regional transfusion center.