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Hepatitis G Virus Infection in Screened Chinese Blood Donors
Author(s) -
Ren FuRong,
Wang Yu,
Li Hui,
Chen HongSong,
Zhao HaiYan
Publication year - 1998
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1046/j.1423-0410.1998.7410051.x
Subject(s) - virology , medicine , hepatitis a virus , virus , hepatitis virus , hepatitis , blood donor , immunology
Background and Objectives: To determine the prevalence of the recently identified hepatitis G virus (HGV)/GBV‐C in screened Chinese paid blood donors. Materials and Methods: Two hundred and seventy‐nine plasma samples were tested for HGV RNA by RT‐PCR with nested primers from the 5'‐noncoding region of GBV‐C. All samples were obtained from plasma or blood bags that had been screened twice by routine selection tests (ALT, HBsAg, Anti‐HCV, anti‐HIV, and syphilis) and were available for clinical use. Results: HGV RNA was detected in 2 (4%) of 50 paid plasma donors from the Beijing Red Cross Blood Center, 1 (2%) of 50 paid blood donors from Taiyuan, and 9 (5%) of 179 paid blood donors from Hebei, a total HGV detection rate of 4.3% (12/279). Conclusions: Our data suggest that HGV infection is relatively frequent even in screened donors, at least in paid screened donors, although larger‐scale studies are required.