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More on False Thrombocytopenias: EDTA‐Dependent Pseudothrombocytopenia Associated with a Congenital Platelet Release Defect
Author(s) -
Silvestri Federico,
Masotti Adriana,
Pradella Paola,
Zaja Francesco,
Barillari Giovanni,
Marco Luigi
Publication year - 1996
Publication title -
vox sanguinis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.68
H-Index - 83
eISSN - 1423-0410
pISSN - 0042-9007
DOI - 10.1046/j.1423-0410.1996.7110027.x
Subject(s) - medicine , platelet , thrombocytopenic purpura , purpura (gastropod) , disease , surgery , pediatrics , ecology , biology
We report herein the case of a 54‐year‐old woman with a moderate bleeding tendency, diagnosed as an EDTA‐dependent pseudothrombocytopenia associated with a congenital platelet release defect. The patient, at the age of 12, had a misleading diagnosis of idiopathic thrombocytopenic purpura and all the recurrent bleeding problems she had during her life were referred to that disease. The recent correct diagnosis of a false thrombocytopenia stimulated further laboratory investigation on the cause of the patient's bleeding tendency with the consequent identification of a congenital platelet deficiency of the arachidonic acid pathway. This finding is of relevant importance for the management of the patient in case of elective surgery or hemorrhagic emergency.