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Crohn's disease post‐cardiac transplantation presenting with severe growth failure and delayed onset of puberty
Author(s) -
Harms Bettina,
Bremner A. Ronald,
Mulligan Jean,
Fairhurst Joanna,
Griffiths D. Mervyn,
Salmon Tony,
Beattie R. Mark
Publication year - 2004
Publication title -
pediatric allergy and immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.269
H-Index - 89
eISSN - 1399-3038
pISSN - 0905-6157
DOI - 10.1046/j.1399-3038.2003.00130.x
Subject(s) - medicine , disease , adult onset still's disease , transplantation , pediatrics , delayed puberty , hormone
We report a 15 yr‐old girl who 10 yr post‐cardiac transplantation presented with severe growth failure and delayed onset of puberty. She was found to have pan‐enteric Crohn's disease and has done remarkably well on principally nutritional therapy with a significant growth spurt and the onset of menarche. The development of bowel disease whilst on immunosuppression is rare and the literature is reviewed.