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Minocycline‐induced central nervous system–pulmonary hypersensitivity syndrome
Author(s) -
Settgast Ann M.,
Groth Travis,
Gertner Elie
Publication year - 2003
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1046/j.1365-4362.2003.01778.x
Subject(s) - medicine , minocycline , vasculitis , complication , acne , hypersensitivity pneumonitis , anti neutrophil cytoplasmic antibody , dermatology , central nervous system , corticosteroid , pneumonitis , immunology , lung , antibiotics , disease , microbiology and biotechnology , biology
Minocycline is widely used in the treatment of acne vulgaris. Reported side‐effects include hypersensitivity pneumonitis, drug‐induced lupus, Antineutrophil Cytoplasmic Antibody (ANCA) ANCA‐positive vasculitis, and other autoimmune syndromes. We report the second case of severe central nervous system–pulmonary syndrome in a patient taking minocycline, which required high‐dose corticosteroid therapy. Clinicians should be aware of this potentially serious complication when prescribing minocycline, or when presented with a systemically ill patient taking this drug.