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Multifocal papillomavirus epithelial hyperplasia: successful treatment with CO 2 laser therapy combined with interferon alpha‐2b
Author(s) -
Akyol Aynur,
Anadolu Rana,
Anadolu Yücel,
Ekmekci Pelin,
Gürgey Erbak,
Akay Nisa
Publication year - 2003
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1046/j.1365-4362.2003.01777.x
Subject(s) - medicine , oral mucosa , hyperplasia , papillomatosis , pathology , human papillomavirus , papilloma , dermatology
Human papilloma virus (HPV) infections of the oral mucosa presents with various clinical and histopathologic features in relation with the causative HPV type and chronicity and the extent of the infection. 1 The entity is known by several names based on histopathologic variations such as focal epithelial hyperplasia, oral florid papillomatosis, verrucous hyperplasia, oral florid verrucosis, and Ackerman's tumor. 2–4 In recent years, the term multifocal papillomavirus epithelial hyperplasia (MPVEH) has been proposed to define the variant that usually occurs in childhood and is characterized by diffuse confluent papillomatous lesions in the oral mucosa. 1 Despite the lesions’ benign appearance, early diagnosis and therapy of MPVEH is essential because of its high capacity for progression and its tendency for malign degeneration. 5–7