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Striated palmoplantar keratoderma of Brunauer‐Fohs–Siemens
Author(s) -
Kotcher Lauren B.,
Jih Ming H.,
White Katherine L.,
KimyaiAsadi Arash
Publication year - 2001
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1046/j.1365-4362.2001.01288.x
Subject(s) - acanthosis , hyperkeratosis , medicine , epidermolytic hyperkeratosis , palmoplantar keratoderma , keratoderma , dermatology , nail (fastener) , dyskeratosis , physical examination , family history , keratolytic , histopathological examination , keratosis , papillomatosis , papule , pathology , surgery , materials science , metallurgy , lesion
A 67‐year‐old African American man presented with callosities of his hands (which he had since adolescence) that were exacerbated by manual labor. His father suffered severe callosities of his feet, but no other family member was afflicted. Physical examination revealed symmetrically distributed linear hyperkeratotic plaques on the palms extending onto the full length of the volar aspect of his digits ( Fig. 1). There was no personal or family history of hair, nail, or dental abnormalities. Histologic evaluation showed marked acanthosis, hypergranulosis, and hyperkeratosis of the lesions ( Fig. 2). There was no evidence of epidermolytic hyperkeratosis. 1Linear hyperkeratotic plaques extending the length of the digits and focally present on the palms2Marked acanthosis, hypergranulosis, and hyperkeratosis of palmoplantar skin (hematoxylin and eosin, × 200)