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Bilateral segmental neurofibromatosis: a case report and review
Author(s) -
Krishnan Ravi S.,
Angel Tiffany A.,
Orengo Ida F.,
Hsu Sylvia
Publication year - 2001
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1046/j.1365-4362.2001.01246-4.x
Subject(s) - medicine , trunk , abdomen , physical examination , neurofibromatosis , papule , hyperpigmentation , neurofibroma , medical history , anatomy , dermatology , surgery , pathology , lesion , ecology , biology
A 65‐year‐old white woman presented with complaints of ‘‘moles’' on the left side of her trunk present for an undetermined period of time. She denied associated pain and pruritus. Her past medical history was significant for hypothyroidism and depression, for which she was taking levothyroxine and venlafaxine, respectively. In addition, she was on hormone replacement therapy. Reportedly, no other family members were affected by similar skin lesions. Physical examination revealed soft, dome‐shaped, skin‐colored papules grouped in a T11–12 dermatomal distribution on her trunk bilaterally. The lesions were more numerous and densely grouped on the right side of her trunk ( Figs 1 and 2). No axillary freckling or café‐au‐lait macules were noted. No Lisch nodules were observed upon ophthalmologic examination. 1Dermatomal distribution of neurofibromas on the right flank2Less obvious dermatomal distribution of neurofibromas on the left abdomen Histologic examination of skin biopsies taken from lesions on both sides of her abdomen in the affected area revealed a proliferation of fusiform cells in a loose fibrous stroma, consistent with neurofibroma.