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Childhood pemphigus
Author(s) -
Wananukul Siriwan,
Pongprasit Prapai
Publication year - 1999
Publication title -
international journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 93
eISSN - 1365-4632
pISSN - 0011-9059
DOI - 10.1046/j.1365-4362.1999.00618.x
Subject(s) - medicine , pemphigus , dermatology
Background Five children with pemphigus are reported: three with pemphigus vulgaris, one with pemphigus vegetans, and one with pemphigus foliaceus. Only one case of juvenile pemphigus vegetans has been published in the literature. Materials and Methods All three patients with pemphigus vulgaris were treated with oral corticosteroid; in two cases, azathioprine was added for steroid‐sparing effect. The patient with pemphigus vegetans had a clinical presentation resembling pemphigus vulgaris, but the lesions in the perianal area healed as hypertrophic granulation tissue. He was treated with oral corticosteroid, azathioprine, and intralesional corticosteroid. The patient with pemphigus foliaceus presented with exfoliative dermatitis, and was treated with oral corticosteroid; methotrexate was added later for steroid‐sparing purposes Results The patients were followed up for 1–4 years; the prognosis of childhood pemphigus is good. Conclusions Long‐term follow‐up is needed to detect flaring of the disease and the side‐effects of immunosuppressive drugs.