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Staining abnormalities of dermal collagen in eosinophil‐ or neutrophil‐rich inflammatory dermatoses of horses and cats as demonstrated with Masson’s trichrome stain
Author(s) -
Fernandez Charlene J.,
Scott Danny W.,
Erb Hollis N.
Publication year - 2000
Publication title -
veterinary dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.744
H-Index - 60
eISSN - 1365-3164
pISSN - 0959-4493
DOI - 10.1046/j.1365-3164.2000.00172.x
Subject(s) - masson's trichrome stain , trichrome stain , trichrome , pathology , eosinophilic , medicine , dermatopathology , staining , degeneration (medical) , cats , eosinophil , h&e stain , immunohistochemistry , asthma
A retrospective study was performed on skin biopsy specimens from horses and cats having eosinophilic granulomas with ‘collagen degeneration’, eosinophilic skin diseases without ‘collagen degeneration’ and pyogranulomas without ‘collagen degeneration’. Neither the appearance of collagen fibres nor the dominant polymorphonuclear cells, as seen in H & E‐stained sections, were predictive of Masson’s trichrome findings. Hence, a Masson’s trichrome staining abnormality of collagen fibres was no more likely to be present in lesions with ‘collagen degeneration’ than in those lesions without ‘collagen degeneration’. In addition, evaluation of trichrome‐stained specimens suggested that there is no collagen degeneration in equine and feline eosinophilic granulomas and that the areas previously referred to as collagen degeneration are more appropriately called flame figures.