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Lymphoma with cutaneous involvement in three domestic rabbits ( Oryctolagus cuniculus )
Author(s) -
White Stephen D.,
Campbell Terry,
Logan Ava,
Meredith Anna,
Schultheiss Patricia,
Van Winkle Tom,
Moore Peter F.,
Naydan Diane K.,
Mallon Francine
Publication year - 2000
Publication title -
veterinary dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.744
H-Index - 60
eISSN - 1365-3164
pISSN - 0959-4493
DOI - 10.1046/j.1365-3164.2000.00159.x
Subject(s) - medicine , lymphoma , isotretinoin , pathology , physiology , dermatology , acne
Three domestic rabbits ( Oryctolagus cuniculus ) with cutaneous lymphoma are described. Two rabbits were young (7 weeks and 1 years) and were euthanized within 1 week of showing clinical signs. Lymphoma was found in the skin and internal organs. The third rabbit was 9.5 years of age, and lived for more than 1 year after diagnosis. No response was seen to either 2 months of alpha‐interferon administration or a 2.5‐week course of isotretinoin treatment. After 1 year the rabbit died suddenly; the owner refused necropsy. Immunologic stains of the tumour in all three rabbits showed T cells to be the lymphoma cell type.