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Systemic lupus erythematosus in a cat: fulfillment of the American Rheumatism Association criteria with supportive skin histopathology
Author(s) -
VITALE CARLO,
IHRKE PETER,
GROSS THELMA LEE,
WERNER LINDA
Publication year - 1997
Publication title -
veterinary dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.744
H-Index - 60
eISSN - 1365-3164
pISSN - 0959-4493
DOI - 10.1046/j.1365-3164.1997.d01-2.x
Subject(s) - histopathology , medicine , rheumatism , dermatology , anti nuclear antibody , atrophy , pathology , immunology , antibody , autoantibody
Systemic lupus erythematosus (SLE) was diagnosed in a 9‐year‐old castrated male Persian cat. The cat described is the first to fulfil four of 11 American Rheumatism Association criteria for the diagnosis of SLE in humans (symmetrical facial dermatitis, thrombocytopenia, positive antinuclear antibodies, oral ulceration) with supportive skin histopathology. Haematological abnormalities included a mild anaemia and severe thrombocytopenia. Skin disease consisted of symmetrical multifocal alopecia with crusting, predominantly on the face. Histopathology of the skin revealed interface dermatitis and interface folliculitis with follicular atrophy. Complete remission was obtained with corticosteroid therapy.