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Glucose‐6‐phosphate dehydrogenase deficiency in northern Vietnam
Author(s) -
Verlé P.,
Nhan D. H.,
Tinh T. T.,
Uyen T. T.,
Thuong N. D.,
Kongs A.,
Stuyft P.,
Coosemans M.
Publication year - 2000
Publication title -
tropical medicine and international health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 114
eISSN - 1365-3156
pISSN - 1360-2276
DOI - 10.1046/j.1365-3156.2000.00542.x
Subject(s) - malaria , foothills , plasmodium falciparum , glucose 6 phosphate dehydrogenase deficiency , ethnic group , glucose 6 phosphate dehydrogenase , glucosephosphate dehydrogenase deficiency , biology , demography , geography , ecology , dehydrogenase , immunology , biochemistry , sociology , anthropology , enzyme
Summary Glucose‐6‐phosphate dehydrogenase (G6PD) deficiency was evaluated in 1676 schoolboys in northern Vietnam. The trait was nearly absent in boys of the Kinh (0.5%) and the Mong (0.7%) ethnic groups that traditionally have lived outside malaria transmission areas. Prevalences among ethnic groups living in the foothills, the breeding area of the main malaria vector Anopheles minimus , ranged from 9.7% to 31%. These findings support the hypothesis of a selective advantage of the trait in Plasmodium falciparum ‐endemic areas.