Premium
Therapeutic efficacy of clindamycin in combination with quinine for treating uncomplicated malaria in a village dispensary in Gabon
Author(s) -
Vaillant Michel,
Millet Pascal,
Luty Adrian,
Tshopamba Paul,
Lekoulou Faustin,
Mayombo Justice,
Georges Alain J.,
Deloron Philippe
Publication year - 1997
Publication title -
tropical medicine and international health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.056
H-Index - 114
eISSN - 1365-3156
pISSN - 1360-2276
DOI - 10.1046/j.1365-3156.1997.d01-411.x
Subject(s) - quinine , clindamycin , malaria , dispensary , medicine , regimen , halofantrine , chloroquine , mefloquine , surgery , antibiotics , immunology , biology , family medicine , microbiology and biotechnology
The efficacy of a 3‐day clindamycin‐quinine regimen to treat clinical malaria attacks was investigated in 256 children from western Gabon. Treatment was well tolerated by all of the children and its efficacy was higher than 97% by day 20. Thus this 3‐day clindamycin‐quinine regimen might constitute a potential alternative to chloroquine for treating clinical malarial attacks in children from Gabon.