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Platelets in Thrombotic and Non‐Thrombotic Disorders
Author(s) -
Gresele P.,
Page C.,
Fuster V.,
Vermylen J.
Publication year - 2003
Publication title -
transfusion medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.471
H-Index - 59
eISSN - 1365-3148
pISSN - 0958-7578
DOI - 10.1046/j.1365-3148.2003.00411.x
Subject(s) - citation , medicine , library science , platelet , computer science
Platelets have attracted increasing interest among clinicians and basic scientists over recent years, and are now known to play a part in many physiological and pathological conditions. In fact, platelets are involved in diseases responsible for the majority of disability and death worldwide, including myocardial infarction, stroke, peripheral vascular disease, cancer, and many infections. Platelets are also studied as a model in many areas of neurobiology, pharmacology, biochemistry and molecular biology. This timely reference provides a comprehensive, detailed, upto-date resource for clinicians and researchers, covering the structure and function of platelets and their role in pharmacology, pathogenesis and therapeutics. It is organized into sections covering platelet physiology, laboratory and methodological issues, platelet involvement in disease, including hemostatic and nonhemostatic conditions, platelet pharmacology, and treatment in the clinic. With contributions from leading authorities including some of the founders of modern platelet studies, this is the definitive reference and guide to the diagnosis and therapeutics of diseases involving platelets. Chapters are devised to provide a critical review of the most clinically relevant aspects of the subject, with extensive references and easy-to-read take-home messages. It will be an essential resource for biomedical scientists and clinicians in hematology, vascular medicine, cardiology, thrombosis and related disciplines.