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Outcome of consecutive pregnancies in a patient with Bombay (O h ) blood group
Author(s) -
Bhattacharya S.,
Makar Y.,
Laycock R. A.,
Gooch A.,
Poole J.,
Hadley A.
Publication year - 2002
Publication title -
transfusion medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.471
H-Index - 59
eISSN - 1365-3148
pISSN - 0958-7578
DOI - 10.1046/j.1365-3148.2002.00407.x
Subject(s) - haemolytic disease , chemiluminescence , medicine , antigen , titer , serology , antibody , obstetrics , pregnancy , andrology , pediatrics , immunology , physiology , gynecology , chemistry , fetus , biology , genetics , organic chemistry
Summary A young lady with a rare Bombay (O h ) blood group had two successive uneventful pregnancies. Her serum contained a potent high‐titre anti‐H and serological as well as chemiluminescence tests, suggesting that the antibody was haemolytic. Her husband was of the normal H status. Theoretically, both babies should have been positive for the H antigen and should have suffered from haemolytic disease of the newborn. This apparent conundrum could be owing to the weak expression of the H antigens on the infant red cells.