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Poster Session: Immunology
Author(s) -
R. A. Dalloul,
O. Folkert,
E. J. Smith,
K. M. Reed,
O. Crasta,
A. P. McElroy,
R. A. Coulombe,
E. A. Wong,
J. B. Dodgson,
D. W. Burt,
D. K. Kim,
H. S. Lillehoj,
S. H. Lee,
S. I. Jang,
C. Ionescu,
D. Bravo,
H. Deng,
X. Guan,
K. B. Gyenai,
J. Xu,
R. Dalloul,
R. M. Gogal,
R. E. Pearson
Publication year - 2001
Publication title -
transfusion medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.471
H-Index - 59
eISSN - 1365-3148
pISSN - 0958-7578
DOI - 10.1046/j.1365-3148.2001.00052.x
Subject(s) - session (web analytics) , medicine , immunology , computer science , world wide web
A community-driven consortium has initiated sequencing the genome of the domesticated turkey, Meleagris gallopavo. Turkey meat is currently the fourth protein choice for American consumers with estimated US production of 271 million birds raised in 2008. In addition to the economic impact, the turkey serves as a model organism for a number of metabolic and medical diseases. The Turkey Genome Sequencing Consortium comprised of US and international scientists has used the latest 454 sequencing technology during this initial phase, with other sequencing platforms to be employed soon. The DNA for sequencing was isolated from a female turkey (NT-WF06-2002-E0010, referred to as “Nici” (Nicholas inbred)). Nici is from an inbred sub-line (sibmating for nine generations) originally derived from a commercially significant breeding line, with 88% monomorphism based on SNP genotyping. Roche/454 GS-Titanium sequencing at Virginia Tech has already produced more than 5x random and paired-end genome coverage (> 8 billion bases sequenced). The latest sequence assembly contains ~880 million base pairs in 428,910 large contigs, with average size of ~2 kb. The expected outcome of the fully sequenced (99% coverage) turkey genome is a rich genomic resource suitable for future academic and industrial, basic and applied poultry research. It will also provide solid foundation for the development of species-specific SNP panels for genome-based selection and improvement, and comparative genomics in poultry and other avian species.