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Retrospective follow‐up of recipients and donors of blood donations reactive for anti‐HBc or for single HCV antibodies
Author(s) -
Howell D. R.,
Webster M. H.,
Barbara J. A. J
Publication year - 2000
Publication title -
transfusion medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.471
H-Index - 59
eISSN - 1365-3148
pISSN - 0958-7578
DOI - 10.1046/j.1365-3148.2000.00266.x
Subject(s) - medicine , blood donations , antibody , infectivity , blood transfusion , blood donor , immunology , retrospective cohort study , virology , hepatitis c virus , hepatitis c , virus
. A retrospective study was undertaken to investigate the infectivity of blood donations that were HCV RIBA indeterminate or reactive for ‘anti‐HBc only’. Samples from 6032 blood donations were tested for anti‐HBc; 17 of them were positive for anti‐HBc but were negative when tested for anti‐HBs. None of the recipients of the red cells from these donations, when tested 9 months after transfusion, had evidence of HBV infection. Samples from 3000 blood donations were tested for HCV antibodies using RIBA‐3; 53 had single lines. Samples taken 9 months after transfusion from the recipients of the red cells from these donations were tested for evidence of infection with hepatitis C, and all were negative.