Premium
In vitro properties of red cells prepared from half‐strength citrate CPD/RAS‐2 (Erythro‐Sol) donations in PL‐146 plastic
Author(s) -
Hornsey,
Jeffrey R. MacDonald,
Drummond,
Trent Walker,
Prowse
Publication year - 2000
Publication title -
transfusion medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.471
H-Index - 59
eISSN - 1365-3148
pISSN - 0958-7578
DOI - 10.1046/j.1365-3148.2000.00229.x
Subject(s) - in vitro , yield (engineering) , andrology , red cell , chemistry , platelet , immunology , medicine , microbiology and biotechnology , food science , biochemistry , biology , materials science , metallurgy
Whole blood donations were collected into 0.5CPD anticoagulant in PL‐146 plastic. This was shown to improve the stability of plasma FVIII levels when compared with CPD. RAS‐2 was used as additive and this improved the in vitro properties of the red cells, such that post processing 2,3‐DPG levels were maintained for 21 days and ATP levels were maintained for 28 days. Whether or not such improvements in red cell properties yield a benefit in clinical use remains to be established.