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Bronchus‐Associated Lymphoid Tissue (BALT) and Larynx‐Associated Lymphoid Tissue (LALT) are Found at Different Frequencies in Children, Adolescents and Adults
Author(s) -
A. S. Hiller,
Thomas Tschernig,
W. J. Kleemann,
Reinhard Pabst
Publication year - 1998
Publication title -
scandinavian journal of immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.934
H-Index - 88
eISSN - 1365-3083
pISSN - 0300-9475
DOI - 10.1046/j.1365-3083.1998.00276.x
Subject(s) - larynx , lymphatic system , pathology , bronchus , biology , medicine , anatomy , lung , respiratory disease
The lung in 98 and the larynx in 51 consecutive autopsies (age: 17th gestational week to 99 years) were studied for the presence of organized lymphoid tissue in the epiglottis and in the wall of larger bronchi. Bronchus‐associated lymphoid tissue (BALT) was seen in about 40% of patients younger than 20 years of age but in older patients only in exceptional cases. In the wall of the epiglottis, however, larynx‐associated lymphoid tissue (LALT) was found at a frequency of ≈80% in patients younger than 20 years and in 56% of the patients older than 20 years. The clinical relevance of LALT as a physiological entry site for antigens or for vaccination protocols using aerosols needs to be studied in further experiments.