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Secretory immune response in patients with intestinal amoebiasis
Author(s) -
ORTIZORTIZ LIBRADO,
MORA NANCY,
ZAMBRANOVILLA SEGIO A.,
CARRERO JULIO CÉSAR,
SÁNCHEZZERPA MARÍA,
OSUNA ANTONIO,
ROSALESBORJAS DISNEY M.
Publication year - 1998
Publication title -
parasite immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.795
H-Index - 75
eISSN - 1365-3024
pISSN - 0141-9838
DOI - 10.1046/j.1365-3024.1998.00173.x
Subject(s) - entamoeba histolytica , saliva , immunology , amoebiasis , immune system , antigen , biology , antibody , western blot , immunoglobulin a , secretory iga , microbiology and biotechnology , immunoglobulin g , biochemistry , gene
The secretory immune response in saliva from intestinal amoebiasis patients against antigens obtained from Entamoeba histolytica membranes was studied. Western blot analysis indicated that patient saliva contains secretory IgA antibodies against antigens with molecular masses ranging from 170 to 24 kDa, some of which were also recognized by saliva from healthy subjects. However, antigens of 170, 125, 46 and 37 kDa are recognized more frequently (> 90%) by the secretory IgA from patients with intestinal amoebiasis than by that from healthy subjects (< 10%) .