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Neonatal respiratory distress syndrome in Karachi: some epidemiological considerations
Author(s) -
Bhutta Zulfiqar Ahmed,
Yusuf Kamran
Publication year - 1997
Publication title -
paediatric and perinatal epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.667
H-Index - 88
eISSN - 1365-3016
pISSN - 0269-5022
DOI - 10.1046/j.1365-3016.1997.d01-9.x
Subject(s) - medicine , respiratory distress , pediatrics , incidence (geometry) , epidemiology , population , mortality rate , infant mortality , neonatal mortality , prospective cohort study , environmental health , surgery , physics , optics
Although respiratory distress syndrome (RDS) is a leading cause of neonatal morbidity and mortality in the west, there are few data on the prevalence and spectrum of RDS from developing countries. Available evidence suggests that the disorder may be less common than the overall 1% incidence reported from developed countries. In a prospective study of the prevalence of RDS in a consecutive 10 134 births at the Aga Khan University Hospital, we documented the disorder in 127 (1.2% births), with a prevalence of 12.8% among low birthweight infants. The overall mortality for this group was 39%, with the highest mortality rate (68%) among newborn infants 1000 g birthweight. Our data from a large and relatively well‐nourished hospital‐born population in Karachi suggest that RDS is a significant cause of morbidity and mortality in preterm infants with a similar prevalence rate to western figures.