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Nifs and Sufs in malaria
Author(s) -
Ellis K. E. S.,
Clough B.,
Saldanha J. W.,
Wilson R. J. M. Iain
Publication year - 2001
Publication title -
molecular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 247
eISSN - 1365-2958
pISSN - 0950-382X
DOI - 10.1046/j.1365-2958.2001.02588.x
Subject(s) - biology , biogenesis , plastid , operon , parasitology , malaria , genome , genetics , computational biology , gene , evolutionary biology , zoology , chloroplast , escherichia coli , immunology
This review assembles data from three bodies of literature (bacterial genetics, plastid biogenesis and parasitology) that seldom have much direct cross‐talk. After overcoming terminological complications to sort out microbial nifS from sufS genes, we connect a bacterial operon, recently found to be involved in iron metabolism, the formation of [Fe–S] clusters and oxidative stress to a potentially important gene ( sufB ) carried on the degenerate plastid genome of malaria and related parasites.