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Repetitive sequences found in the chromosome of the myxobacterium Nannocystis exedens are similar to msDNA: a possible retrotransposition event in bacteria
Author(s) -
Lampson Bert C.,
Rice Scott A.
Publication year - 1997
Publication title -
molecular microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.857
H-Index - 247
eISSN - 1365-2958
pISSN - 0950-382X
DOI - 10.1046/j.1365-2958.1997.2671627.x
Subject(s) - biology , retrotransposon , genetics , chromosome , event (particle physics) , computational biology , transposable element , genome , gene , physics , quantum mechanics
The first reverse transcriptase (RT) to be found in a prokaryotic cell is encoded by an element called a retron which resides in the chromosome of many different bacteria. In addition, all retrons code for a functionally obscure RNA–DNA satellite molecule called msDNA. msDNA is synthesized from an RNA template by the retron‐encoded RT. An unusual retron element is described here from the myxobacterium Nannocystis exedens . This retron does not appear to have a typical RT gene in close proximity (1 kb) to the gene msd (which encodes the DNA strand of msDNA). The gene msr (which encodes the RNA strand of msDNA) appears to be duplicated and flanks both sides of the msd gene. Also discovered throughout the chromosome of this bacterium is a set of repeated sequences related to msDNA. These repeat sequences match only part of the sequence of msDNA and may have become incorporated into the chromosome of this bacterium by reverse transcription.